Label-free profiling of skeletal muscle using high-definition mass spectrometry
نویسندگان
چکیده
منابع مشابه
Mass Spectrometry-Based Label-Free Quantitative Proteomics
In order to study the differential protein expression in complex biological samples, strategies for rapid, highly reproducible and accurate quantification are necessary. Isotope labeling and fluorescent labeling techniques have been widely used in quantitative proteomics research. However, researchers are increasingly turning to label-free shotgun proteomics techniques for faster, cleaner, and ...
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To address the challenges associated with differential expression proteomics, label-free mass spectrometric protein quantification methods have been developed as alternatives to array-based, gel-based, and stable isotope tag or label-based approaches. In this paper, we focus on the issues associated with label-free methods that rely on quantitation based on peptide ion peak area measurement. Th...
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ژورنال
عنوان ژورنال: PROTEOMICS
سال: 2014
ISSN: 1615-9853
DOI: 10.1002/pmic.201400118